Nerve block may cut opioid use after heart bypass

NCT ID NCT07732465

Not yet recruiting Symptom relief Sponsor: Montreal Heart Institute Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial tests whether a targeted nerve block, called an adductor canal block, can reduce leg pain after coronary artery bypass grafting (CABG) when a leg vein is used as a graft. About 120 adults scheduled for CABG will receive either the block with a numbing medication or a sham injection. Researchers will measure leg pain at rest over the first 24 hours and track total opioid use for 48 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a nerve block injection with bupivacaine and dexmedetomidine
What this could lead to: If effective, this nerve block could offer a simple way to ease leg pain after heart bypass surgery and reduce reliance on opioid painkillers.
What could go wrong: This is a mid-stage trial with 120 participants, so results may not apply to all patients. The block carries small risks like infection or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY BYPASS GRAFTING (CABG) SURGERY SAPHENECTOMY

Contacts and locations

Locations

Montreal Heart Institute

Montreal, Quebec, H1T 1C8, Canada

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