Which diabetes pill works best as a third option?

NCT ID NCT03499704

First seen Mar 25, 2026 · Last updated May 08, 2026 · Updated 7 times

Summary

This study tested whether adding pioglitazone or dapagliflozin to two common diabetes drugs (alogliptin and metformin) helps lower blood sugar more effectively. It involved 133 adults with type 2 diabetes whose blood sugar was not well controlled. The main goal was to see if one combination was not worse than the other after 26 weeks.

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Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, Gyeonggi-do, 16499, South Korea

  • Chosun University Hospital

    Gwangju, 61453, South Korea

  • Daejeon Eulji Medical Center, Eulji University

    Daejeon, 35233, South Korea

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Kangbuk Samsung Hospital

    Seoul, 03181, South Korea

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • Kyung Hee University Hospital at Gangdong

    Seoul, 05278, South Korea

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • The Catholic University of Korea, Bucheon, St. Marys Hospital

    Bucheon-si, Gyeonggi-do, 14647, South Korea

  • The Catholic University of Korea, ST. Vincents Hospital

    Suwon, Gyeonggi-do, 16247, South Korea

  • Ulsan University Hospital

    Ulsan, 44033, South Korea

  • YeungNam University Hospital

    Daegu, 42415, South Korea

  • Yonsei University Health System Severance Hospital

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.