Protein test may spot preeclampsia risk in High-Risk pregnancies
NCT ID NCT04319341
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study examined whether measuring a protein called ADAMTS13 in early pregnancy can help predict preeclampsia in women with antiphospholipid antibody syndrome (APS). Researchers analyzed stored blood samples from 513 women in the NOH-APS cohort who became pregnant after their APS diagnosis. The goal was to see if ADAMTS13 activity, antigen levels, or autoantibodies were linked to later development of preeclampsia or related complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a blood test that helps predict preeclampsia risk early in pregnancy for women with antiphospholipid antibody syndrome.
What could go wrong
This is an observational study using stored samples, not a treatment trial. It may not prove that ADAMTS13 directly causes or prevents preeclampsia.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU de Nîmes - Hôpital Universitaire Carémea
Nîmes, 30029, France