Could a common drug stop Parkinson's before it starts?

NCT ID NCT06996652

Summary

This study is testing if a drug called adalimumab can slow or stop the brain changes that lead to Parkinson's disease in people with REM Sleep Behavior Disorder (RBD). About 108 people with RBD will receive either the drug or a placebo for 96 weeks. Researchers will use brain scans and other tests to see if the treatment can prevent the progression to Parkinson's.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

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  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

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  • Cleveland Clinic Lou Ruvo Center for Brain Health - Las Vegas

    Las Vegas, Nevada, 89106, United States

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  • Dartmouth Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

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  • Emory University School of Medicine

    Atlanta, Georgia, 30329, United States

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  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

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  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

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  • Medical University of South Carolina

    Charleston, South Carolina, 29403, United States

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  • Montreal Neurological Institute-Hospital at McGill University

    Montreal, Quebec, H3A 2B4, Canada

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  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

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  • Parkinson's Disease & Movement Disorders Center of Boca Raton

    Boca Raton, Florida, 33486, United States

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  • University of Colorado Anschutz

    Aurora, Colorado, 80045, United States

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  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

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  • University of Minnesota

    Minneapolis, Minnesota, 55414, United States

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  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19107, United States

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  • University of Texas Health Science Center- San Antonio

    San Antonio, Texas, 78229, United States

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  • University of Texas Houston Medical Center

    Houston, Texas, 77030, United States

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  • Washington University

    St Louis, Missouri, 63110, United States

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  • Weill Medical College of Cornell University

    New York, New York, 10021, United States

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  • Yale Medicine

    North Haven, Connecticut, 06473, United States

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Conditions

Explore the condition pages connected to this study.