New cell therapy trial hopes to tackle recurrent brain cancer

NCT ID NCT06254326

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial is testing a personalized cell therapy for adults with recurrent oligodendroglioma, a type of brain tumor. The treatment involves taking a patient's own immune cells and stem cells, modifying them in the lab, and giving them back to fight the tumor. The main goals are to see if this approach is safe and feasible, with only 12 participants planned.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

personalized cell therapy (dendritic cell vaccines, tumor-reactive T cells, and stem cells)

What this could lead to

If successful, this could point toward a new treatment option for recurrent oligodendroglioma, a type of brain tumor that is hard to treat.

What could go wrong

This is a very early Phase 1 trial with only 12 participants, so it is primarily testing safety and feasibility. The treatment is complex and may cause severe side effects, and it is not yet known if it will help control the tumor.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer IDH-mutant and 1p/19q-codeleted oligodendroglioma oligodendroglioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Florida Health Shands Hospital

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact