Acupuncture needles take on Chemo's nerve damage
NCT ID NCT07693335
First seen Jul 09, 2026 · Last updated Jul 14, 2026 · Updated 3 times
Summary
This study tests whether acupuncture can reduce the nerve pain, numbness, and tingling that often lingers after chemotherapy. Cancer survivors who completed chemo at least three months ago will receive either real acupuncture, a sham (fake) version, or no extra treatment. The goal is to see if real acupuncture improves symptoms more than placebo or doing nothing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- acupuncture
- What this could lead to
- If it works, this could offer a drug-free way to manage chemotherapy-induced nerve damage, improving daily comfort and function.
- What could go wrong
- This is a small, early-phase trial, so results may not apply widely. The sham acupuncture group helps control for placebo, but real-world benefits could be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
28 people
The number who actually took part.
- Started
-
Mar 2021
- Finished
-
Jun 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
The study will enroll patients with a symptom of peripheral neuropathy, including paresthesia, numbness, glove-and-stocking sensory loss distribution or pain in four limbs, and meet the following inclusion criteria: Inclusion Criteria: * 1\. All adult cancer patients (Age≧20-year-old) who received chemotherapy regimens, including adjuvant and neoadjuvant therapy * 2\. Stage I-III cancer patients * 3\. Completed chemotherapy regimens more than 3 months, including Taxanes (paclitaxel or docetaxel), platinum (cisplatin, oxaliplatin, carboplatin) * 4\. Baseline von Frey Monofilament test (Target force at hand) ≧ 0.07gms * 5\. Baseline von Frey Monofilament test (Target force at foot) ≧ 0.4gms * 6\. Eastern Cooperative Oncology Group (ECOG) performance status ≦3 * 7\. Grading of peripheral sensory neuropathy in National Cancer Institute- common terminology criteria for adverse events,v5.0 (NCI-CTCAE5) ≧1 * 8\. Patients were restricted acupuncture treatment for one month before recruitment * 9\. Written patient informed consent Exclusion Criteria: * 1\. Uncontrolled Diabetic Mellitus, HbA1c≧7% is inappropriate\[19\]. * 2\. Diabetic neuropathy diagnosed before receiving chemotherapy * 3\. Neuropathy from any type of nerve compression (e.g., carpal/tarsal tunnel syndrome, radiculopathy, spinal stenosis, brachial plexopathy) * 4\. Concomitant with duloxetine, or another analgesia, including Pregabalin, Venlafaxine, Minocycline, Topical gel, Oxycodone, Naloxone, Cannabinoids, and Angiotensin II type 2 receptor antagonist * 5\. Severe hemorrhagic coagulopathy or bleeding tendency * 6\. Unstable cardiovascular disease * 7\. Severe skin lesions around the treatment sites The researchers will exclude any participants considered to be inappropriate for the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
An Nan Hospital, China Medical University
Tainan, Taiwan, 709, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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