Acupuncture needles take on Chemo's nerve damage

NCT ID NCT07693335

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study tests whether acupuncture can reduce the nerve pain, numbness, and tingling that often lingers after chemotherapy. Cancer survivors who completed chemo at least three months ago will receive either real acupuncture, a sham (fake) version, or no extra treatment. The goal is to see if real acupuncture improves symptoms more than placebo or doing nothing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acupuncture
What this could lead to
If it works, this could offer a drug-free way to manage chemotherapy-induced nerve damage, improving daily comfort and function.
What could go wrong
This is a small, early-phase trial, so results may not apply widely. The sham acupuncture group helps control for placebo, but real-world benefits could be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

28 people

The number who actually took part.

Started

Mar 2021

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

The study will enroll patients with a symptom of peripheral neuropathy, including paresthesia, numbness, glove-and-stocking sensory loss distribution or pain in four limbs, and meet the following inclusion criteria: Inclusion Criteria: * 1\. All adult cancer patients (Age≧20-year-old) who received chemotherapy regimens, including adjuvant and neoadjuvant therapy * 2\. Stage I-III cancer patients * 3\. Completed chemotherapy regimens more than 3 months, including Taxanes (paclitaxel or docetaxel), platinum (cisplatin, oxaliplatin, carboplatin) * 4\. Baseline von Frey Monofilament test (Target force at hand) ≧ 0.07gms * 5\. Baseline von Frey Monofilament test (Target force at foot) ≧ 0.4gms * 6\. Eastern Cooperative Oncology Group (ECOG) performance status ≦3 * 7\. Grading of peripheral sensory neuropathy in National Cancer Institute- common terminology criteria for adverse events,v5.0 (NCI-CTCAE5) ≧1 * 8\. Patients were restricted acupuncture treatment for one month before recruitment * 9\. Written patient informed consent Exclusion Criteria: * 1\. Uncontrolled Diabetic Mellitus, HbA1c≧7% is inappropriate\[19\]. * 2\. Diabetic neuropathy diagnosed before receiving chemotherapy * 3\. Neuropathy from any type of nerve compression (e.g., carpal/tarsal tunnel syndrome, radiculopathy, spinal stenosis, brachial plexopathy) * 4\. Concomitant with duloxetine, or another analgesia, including Pregabalin, Venlafaxine, Minocycline, Topical gel, Oxycodone, Naloxone, Cannabinoids, and Angiotensin II type 2 receptor antagonist * 5\. Severe hemorrhagic coagulopathy or bleeding tendency * 6\. Unstable cardiovascular disease * 7\. Severe skin lesions around the treatment sites The researchers will exclude any participants considered to be inappropriate for the study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • An Nan Hospital, China Medical University

    Tainan, Taiwan, 709, Taiwan

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