Can a patch, therapy, and brain zapping help people on opioids for chronic pain?

NCT ID NCT06442566

First seen Nov 05, 2025 · Last updated May 18, 2026 · Updated 29 times

Summary

This study is for adults with chronic pain who have been taking daily prescription opioids for at least 3 months. It tests three approaches in sequence: a low-dose buprenorphine patch, a brief pain-focused cognitive behavioral therapy, and a type of brain stimulation called rTMS. The goal is to see if these treatments can reduce pain, improve quality of life, and lower the risks of long-term opioid use. About 240 participants will be followed for up to a year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29407, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

Conditions

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