New study aims to curb opioid risks while easing chronic pain

NCT ID NCT06442566

First seen Nov 05, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study is for adults with chronic pain who have been taking prescription opioids for at least 90 days and face extra risks like using sedatives or having a substance use disorder. Researchers will test three steps in sequence: switching to a low-dose buprenorphine patch, adding a brief pain-focused therapy, and then using a non-invasive brain stimulation technique. The goal is to see if these steps can reduce pain, improve quality of life, and lower the chances of opioid-related harm.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29407, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.