New hope for CLL patients who Can't tolerate standard treatment

NCT ID NCT02717611

First seen Jan 08, 2026 · Last updated Apr 30, 2026 · Updated 14 times

Summary

This study tests a drug called acalabrutinib (ACP-196) in 60 adults with chronic lymphocytic leukemia (CLL) that has come back or not responded to treatment, and who had side effects from ibrutinib. The main goal is to see how many people's tumors shrink or disappear. Participants take the drug by mouth and are followed for disease progression and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Tucson, Arizona, 85704, United States

  • Research Site

    Concord, California, 94520, United States

  • Research Site

    La Jolla, California, 92093, United States

  • Research Site

    Palo Alto, California, 94304, United States

  • Research Site

    Washington D.C., District of Columbia, 20007, United States

  • Research Site

    Chicago, Illinois, 60611, United States

  • Research Site

    Lake Success, New York, 11042, United States

  • Research Site

    New York, New York, 10021, United States

  • Research Site

    Columbus, Ohio, 43210, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Sherman, Texas, USA, United States

  • Research Site

    Seattle, Washington, 98108, United States

  • Research Site

    Seattle, Washington, 98122, United States

  • Research Site

    Spokane, Washington, 99208, United States

  • Research Site

    Milwaukee, Wisconsin, 53226, United States

  • Research Site

    Bruges, 8000, Belgium

  • Research Site

    Bordeaux, 33076, FR, France

  • Research Site

    Haifa, 31000, Israel

  • Research Site

    Madrid, 28006, Spain

  • Research Site

    Bournemouth, BH7 7DW, United Kingdom

  • Research Site

    Leeds, LS9 7TF, United Kingdom

  • Research Site

    Manchester, M20 4BX, United Kingdom

Conditions

Explore the condition pages connected to this study.