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Extra knee stabilization: key to faster muscle recovery after ACL surgery?

NCT ID NCT07777458

Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial tests whether adding a procedure called lateral extra-articular tenodesis (LET) to standard ACL reconstruction affects leg muscle recovery. Participants are adults with acute ACL injuries scheduled for surgery. Half will receive standard ACL reconstruction, and half will receive the same surgery plus LET. Researchers will compare changes in leg lean mass at 9 months after surgery to see if LET helps or hinders muscle recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lateral Extra-Articular Tenodesis (LET) — a procedure using a strip of the iliotibial band to stabilize the knee, added to standard ACL reconstruction.
What this could lead to
If LET proves beneficial, it could become a standard addition to ACL surgery, improving knee stability and muscle recovery for patients.
What could go wrong
This is a small, early-stage trial, so results may not apply broadly. Adding LET might not improve recovery and could even lead to greater muscle loss.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Aug 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Skeletally mature patients less than or equal to 60 years of age with ACL insufficiency scheduled to undergo primary BTB ACL reconstruction with or without LET. * Patients presenting with acute ACL injuries. Patients presenting with acute ACL injuries will be eligible for enrollment. * Acute injuries will be defined as injuries occurring within 6 weeks of presentation. Exclusion Criteria: * undergoing multi ligamentous reconstruction (PCL, MCL, or PLC) * revision ACL reconstruction * neuromuscular disorders * contralateral ACL injury * pregnant or nursing * unable to read or write in English * possessing a high likelihood of remaining non-compliant * desire to return to sport prior to 6 months.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament reconstruction (ACLR)

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States