ACL surgery showdown: which graft works best?

NCT ID NCT06668155

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two surgical methods for repairing a torn ACL: using a graft from your own tendon (autograft) versus using donor tissue plus an extra stabilizing procedure (allograft with LET). The goal is to see which approach leads to better knee stability, strength, and healing. Sixty adults with ACL-deficient knees will be randomly assigned to one of the two groups and followed for at least a year.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
surgical procedure (autograft or allograft with lateral extra-articular tenodesis)
What this could lead to
If successful, this could show that using donor tissue with extra stabilization works as well as or better than using your own tissue for ACL reconstruction, potentially reducing recovery time and surgical site pain.
What could go wrong
This is a small, early-stage trial with only 60 people, so results may not apply to everyone. Both procedures are surgeries with standard risks like infection, graft failure, or stiffness.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.