Brain may 'forget' to use healed leg after ACL surgery, study suggests

NCT ID NCT04837417

First seen Nov 18, 2025 · Last updated May 13, 2026 · Updated 19 times

Summary

This study looked at 10 people who had ACL knee surgery 6 to 18 months earlier. Researchers wanted to understand why leg muscle weakness often continues even after healing. They tested whether the brain unconsciously stops fully using the injured leg—a pattern called 'learned non-use'—and whether brain activity differences play a role. The goal is to find better ways to guide return to sports and design future rehab programs.

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Contacts and locations

Locations

  • ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Presidio Ospedaliero Gaetano Pini

    Milan, Italy

  • Istituto Auxologico Italiano

    Milan, MI, 20121, Italy

Conditions

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