New gout drug aims to beat pain faster than standard treatment

NCT ID NCT07145229

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This Phase 2 trial tests an experimental drug called ABP-745 against colchicine (a standard gout medicine) and a placebo in 380 adults with acute gout flares. The goal is to see if ABP-745 reduces pain and swelling better than current options. Participants will take tablets and report their pain levels over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ABP-745 (an experimental drug) and colchicine (standard gout medication)

What this could lead to

If successful, ABP-745 could offer a new option for quickly reducing pain and swelling during an acute gout flare.

What could go wrong

This is an early Phase 2 trial with only 380 participants, so results may not apply to everyone. The drug may not work better than existing treatments or could have unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gout

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albuquerque Clinical Trials, Inc.

    RECRUITING

    Albuquerque, New Mexico, 87176, United States

  • Bioluminux Clinical Research

    RECRUITING

    Naperville, Illinois, 60540, United States

  • Canopy Clinical Research Altona North

    RECRUITING

    North Altona, Victoria, 3025, Australia

  • Canopy Clinical Research Northern Beaches

    RECRUITING

    Brookvale, New South Wales, 2100, Australia

  • Chengdu Fifth People's Hospital

    RECRUITING

    Chengdu, Sichuan, 610000, China

  • DelRicht Research

    RECRUITING

    Baton Rouge, Louisiana, 70769, United States

  • DelRicht Research

    RECRUITING

    New Orleans, Louisiana, 70115, United States

  • DelRicht Research

    RECRUITING

    Tulsa, Oklahoma, 74133, United States

  • DelRicht Research Gulfport

    RECRUITING

    Gulfport, Mississippi, 39501, United States

  • Emeritus Melbourne

    RECRUITING

    Camberwell, Victoria, 3124, Australia

  • Emeritus Sydney

    RECRUITING

    Botany, New South Wales, 2019, Australia

  • Evergreen Clinical Trial

    NOT_YET_RECRUITING

    Norcross, Georgia, 30003, United States

  • Exinia Research

    RECRUITING

    La Mesa, California, 91942, United States

  • Exinia Research

    RECRUITING

    Des Moines, Iowa, 50308, United States

  • Genesis Research Services

    RECRUITING

    Newcastle, New South Wales, 2019, Australia

  • Hangzhou First People's Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

  • Hebei Petro China Central Hospital

    RECRUITING

    Langfang, Hebei, 065000, China

  • Huai'an First People's Hospital

    RECRUITING

    Huai'an, Jiangsu, 223000, China

  • Huashan Hospital, Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200040, China

  • Interphase Clinical Trials

    RECRUITING

    Lutherville, Maryland, 21093, United States

  • Linfen Central hospital

    RECRUITING

    Linfen, Shanxi, 041000, China

  • Northshore Research Associates

    RECRUITING

    Alexandria, Louisiana, 71303, United States

  • Novatrials

    RECRUITING

    Kotara, New South Wales, 2289, Australia

  • Onyx Clinical Research

    RECRUITING

    Peoria, Arizona, 61636, United States

  • Peking University Third hospital

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

  • Pingxiang People's Hospital

    RECRUITING

    Pingxiang, Jiangxi, 337000, China

  • Premier Family Physicians

    NOT_YET_RECRUITING

    Austin, Texas, 78734, United States

  • Shaanxi Provincial People's Hospital

    RECRUITING

    Xi’an, Shanxi, 710000, China

  • Shanxi Bethune Hospital

    RECRUITING

    Taiyuan, Shanxi, 030000, China

  • The second affiliated hospital of guangxi medical university

    RECRUITING

    Nanning, Guangxi, 530000, China

  • Wenzhou People's Hospital

    RECRUITING

    Wenzhou, Zhejiang, 325000, China

  • West Clinical Research

    NOT_YET_RECRUITING

    Morehead City, North Carolina, 28557, United States

  • Wuhan UHospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

  • Xi'an Daxing Hospital

    RECRUITING

    Xi’an, Shanxi, 710000, China

  • Xiangtan Central Hospital

    RECRUITING

    Xiangtan, Hunan, 411100, China

  • Xiangya Hospital Zhuzhou Central South University

    RECRUITING

    Zhuzhou, Hunan, 412000, China

  • Xuanwu Hospital Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

  • Zaozhuang Municipal Hospital

    RECRUITING

    Zaozhuang, Shandong, 277100, China