New hope for rare blood cancers: international trial tests smart drug cocktails

NCT ID NCT04061421

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests new combinations of drugs for people with MDS/MPN, a group of rare blood cancers. The goal is to find safe and effective doses of these drug combos to better control the disease. About 94 adults will take part, receiving an oral drug called ASTX727 plus another targeted therapy.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moffitt Cancer Center

    SUSPENDED

    Tampa, Florida, 33612, United States

  • Oregon Health Sciences University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

  • University of Rochester Wilmot Cancer Institute

    RECRUITING

    Rochester, New York, 14609, United States

    Contact Email: •••••@•••••

  • Vanderbilt-Ingram Cancer Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.