New antibody drug takes aim at Hard-to-Treat cancers

NCT ID NCT06126666

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing a new drug called ABL103 in people with advanced solid tumors that have not responded to standard treatments. The drug is a bispecific antibody designed to help the immune system attack cancer cells. The study will enroll 96 participants to evaluate safety, dosing, and any signs of tumor shrinkage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ABL103 (a bispecific antibody that targets two proteins on cancer cells to boost immune response)

What this could lead to

If successful, this could lead to a new treatment option for people with advanced solid tumors who have run out of standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 96 participants, so it is primarily testing safety and dosing. The drug may not shrink tumors or may cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam, Seoul, 13620, South Korea

    Contact

    Contact Email: •••••@•••••

  • Seoul National University Hospital

    NOT_YET_RECRUITING

    Seoul, Seoul, 03080, South Korea

    Contact Email: •••••@•••••

  • Sevrance Hospital

    RECRUITING

    Seoul, South Korea, 03722, South Korea

    Contact Email: •••••@•••••