New hope for NF1 patients: drug may shrink painful nerve tumors without surgery

NCT ID NCT04750928

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 29 times

Summary

This study tests a drug called abemaciclib for people with NF1 who have atypical neurofibromas—nerve tumors that can cause pain and other problems. The goal is to find a safe dose that can shrink or control these tumors without surgery. About 55 participants aged 12 and older will take the drug twice daily for up to 2 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.