Stem cell trial aims to heal wounds in 'Butterfly Skin' disease
NCT ID NCT05838092
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether ABCB5-positive stem cells given through an IV can safely and effectively heal wounds in people with epidermolysis bullosa, a rare genetic condition that causes fragile, blistering skin. The study includes 9 participants with a specific type of the disease (recessive dystrophic EB) and compares the stem cells to a placebo. The main goal is to see if the target wound closes completely.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ABCB5-positive mesenchymal stromal cells (stem cells)
What this could lead to
If it works, this could point toward a treatment that helps heal wounds in people with epidermolysis bullosa, a severe skin condition.
What could go wrong
This is a very small early-stage trial with only 9 participants, so results may not apply to everyone. The treatment may not work better than placebo, and there could be side effects from the stem cells.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Masonic Cancer Center and Medical Center Minneapolis
Minneapolis, Minnesota, 55455, United States