New drug combo shows promise in early cancer trial
NCT ID NCT02988960
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests two experimental immunotherapy drugs, ABBV-927 and ABBV-181, in people with advanced solid tumors that have not responded to other treatments. The main goal is to find the safest dose and understand how the drugs move through the body. About 163 participants will receive the drugs alone or together, and researchers will monitor side effects and any tumor shrinkage.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Austin Health /ID# 171189
Heidelberg, Victoria, 3084, Australia
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Carolina BioOncology Institute /ID# 155265
Huntersville, North Carolina, 28078, United States
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Centre Leon Berard /ID# 162663
Lyon, Rhone, 69373, France
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Duplicate_Institut Regional du Cancer /ID# 163609
Montpellier, Herault, 34298, France
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Hospital Universitario Fundacion Jimenez Diaz /ID# 200128
Madrid, 28040, Spain
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Hospital Universitario HM Sanchinarro /ID# 200127
Madrid, 28050, Spain
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Hospital Universitario Puerta de Hierro - Majadahonda /ID# 200129
Majadahonda, Madrid, 28222, Spain
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Hospital Universitario y Politecnico La Fe /ID# 200975
Valencia, 46026, Spain
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Institut Bergonie /ID# 162665
Bordeaux, Gironde, 33000, France
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Institut Gustave Roussy /ID# 162666
Villejuif, Val-de-Marne, 94805, France
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Massachusetts General Hospital /ID# 155267
Boston, Massachusetts, 02114, United States
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National Cancer Center Hospital /ID# 217758
Chuo-ku, Tokyo, 104-0045, Japan
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National Cancer Center Hospital East /ID# 216870
Kashiwa-shi, Chiba, 277-8577, Japan
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Peninsula Oncology Centre /ID# 164372
Frankston, Victoria, 3199, Australia
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Seoul National University Hospital /ID# 166291
Seoul, Seoul Teugbyeolsi, 03080, South Korea
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Tennessee Oncology-Nashville Centennial /ID# 158654
Nashville, Tennessee, 37203-1632, United States
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The Angeles Clinic and Researc /ID# 156324
Los Angeles, California, 90025, United States
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The University of Chicago Medical Center /ID# 155264
Chicago, Illinois, 60637-1443, United States
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University Health Network_Princess Margaret Cancer Centre /ID# 200819
Toronto, Ontario, M5G 2M9, Canada
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University of Texas MD Anderson Cancer Center /ID# 155263
Houston, Texas, 77030, United States
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Virginia Cancer Specialists - Fairfax /ID# 155266
Fairfax, Virginia, 22031, United States
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Yonsei University Health System Severance Hospital /ID# 166292
Seoul, 03722, South Korea
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