New drug shows promise in slowing early Alzheimer's

NCT ID NCT05291234

First seen Dec 12, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tested an experimental drug called ABBV-916 in people with early Alzheimer's disease. The goal was to see if it is safe and can slow down the disease. About 106 participants received either the drug or a placebo through an IV every 4 weeks for 6 months, with an option to continue for 2 more years. The study looked at side effects, how the drug moves in the body, and changes in brain amyloid plaques.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advanced Memory Research Institute of NJ /ID# 239533

    Toms River, New Jersey, 08755-5043, United States

  • Allied Biomedical Res Inst Inc /ID# 244823

    Miami, Florida, 33155, United States

  • Alzheimer's Research and Treatment Center - Stuart /ID# 245477

    Stuart, Florida, 34997-5765, United States

  • Alzheimer's Research and Treatment Center - Wellington /ID# 245201

    Wellington, Florida, 33414, United States

  • Artemis Institute for Clinical Research - San Diego /ID# 244508

    San Diego, California, 92103-2204, United States

  • Aventura Neurological Associates /ID# 243892

    Aventura, Florida, 33180, United States

  • Charter Research - Lady Lake /ID# 244657

    Lady Lake, Florida, 32162, United States

  • Charter Research - Winter Park /ID# 244778

    Orlando, Florida, 32803-1839, United States

  • ClinCloud - Maitland /ID# 244507

    Maitland, Florida, 32751, United States

  • ClinCloud LLC - Viera/Melbourne /ID# 240635

    Melbourne, Florida, 32940-8288, United States

  • Clinical Site Partners (CSP) - Orlando /ID# 245127

    Winter Park, Florida, 32789-4681, United States

  • Clinical Trials of Texas, Inc /ID# 244917

    San Antonio, Texas, 78229, United States

  • Columbus Memory Center /ID# 245054

    Columbus, Georgia, 31909, United States

  • Conquest Research /ID# 243916

    Winter Park, Florida, 32789, United States

  • Finlay Medical Research /ID# 245996

    Miami, Florida, 33126, United States

  • Headlands Research - Orlando /ID# 239119

    Orlando, Florida, 32819, United States

  • IMIC Inc. Medical Research /ID# 245900

    Palmetto Bay, Florida, 33157, United States

  • Irvine Clinical Research /ID# 239469

    Irvine, California, 92614, United States

  • JEM Research Institute /ID# 239122

    Lake Worth, Florida, 33462-1141, United States

  • K2 Medical Research - Ocoee /ID# 246849

    Ocoee, Florida, 34761-4547, United States

  • K2 Medical Research - Orlando - South Orlando Avenue /ID# 243919

    Orlando, Florida, 32751, United States

  • Keystone Clinical Studies LLC /ID# 239973

    Plymouth Meeting, Pennsylvania, 19462, United States

  • Merritt Island Medical Research /ID# 239495

    Merritt Island, Florida, 32952-3616, United States

  • Neurology Associates Ormond Beach /ID# 245527

    Ormond Beach, Florida, 32174, United States

  • Optimus U /ID# 245868

    Miami, Florida, 33125-4013, United States

  • Pacific Research Network, Inc. /ID# 244083

    San Diego, California, 92103, United States

  • Premiere Research Institute - Palm Beach /ID# 240108

    West Palm Beach, Florida, 33407-3209, United States

  • QUEST Research Institute /ID# 239459

    Farmington Hills, Michigan, 48334-2977, United States

  • Re:Cognition Health - Fairfax VA /ID# 239501

    Fairfax, Virginia, 22031-5207, United States

  • Renstar Medical Research /ID# 240153

    Ocala, Florida, 34470, United States

  • Syrentis Clinical Research /ID# 239682

    Santa Ana, California, 92705, United States

  • Tucson Neuroscience Research /ID# 244957

    Tucson, Arizona, 85710-6152, United States

Conditions

Explore the condition pages connected to this study.