Experimental cancer drug combo trial halted early

NCT ID NCT06158958

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This early-stage study tested an experimental drug called ABBV-303, alone or with another drug (budigalimab), in adults with advanced solid tumors that had stopped responding to treatment. The goal was to check safety and see if the drugs could shrink tumors. The study was terminated early after enrolling 27 participants out of a planned 181.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Carolina BioOncology Institute /ID# 254305

    Huntersville, North Carolina, 28078, United States

  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 266792

    Irvine, California, 92618, United States

  • City of Hope /ID# 254303

    Duarte, California, 91010, United States

  • Hadassah Medical Center-Hebrew University /ID# 254606

    Jerusalem, 91120, Israel

  • NEXT Oncology /ID# 257395

    San Antonio, Texas, 78229, United States

  • NYU Langone - Laura and Isaac Perlmutter Cancer Center /ID# 256943

    New York, New York, 10016, United States

  • National Cancer Center Hospital /ID# 254359

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East /ID# 261712

    Kashiwa-shi, Chiba, 277-8577, Japan

  • Rambam Health Care Campus /ID# 254608

    Haifa, 3109601, Israel

  • START Midwest /ID# 256945

    Grand Rapids, Michigan, 49546-7062, United States

  • Shizuoka Cancer Center /ID# 261714

    Sunto-gun, Shizuoka, 411-8777, Japan

  • South Texas Accelerated Research Therapeutics /ID# 256944

    San Antonio, Texas, 78229, United States

  • The Chaim Sheba Medical Center /ID# 259408

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The Ohio State University - The James /ID# 260475

    Columbus, Ohio, 43210-1240, United States

  • University of Southern California /ID# 254356

    Los Angeles, California, 90033, United States

  • University of Texas MD Anderson Cancer Center /ID# 254308

    Houston, Texas, 77030, United States

  • Wakayama Medical University Hospital /ID# 254361

    Wakayama, Wakayama, 641-8510, Japan

  • Washington University-School of Medicine /ID# 262943

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.