New combo therapy may help some hepatitis b patients stop daily pills
NCT ID NCT04980482
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times
Summary
This study tested a new drug called AB-729 combined with standard antiviral therapy and short courses of pegylated interferon in 43 adults with chronic hepatitis B. The goal was to see if the combination is safe and can lower hepatitis B surface antigen levels enough that patients might be able to stop their daily antiviral pills. Participants had well-controlled virus levels at the start and were followed for side effects and changes in viral markers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Arensia Exploratory Medicine Moldova
Chisinau, 2025, Moldova
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Arizona Liver Health
Chandler, Arizona, 85224, United States
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Arizona Liver Health
Tucson, Arizona, 85712, United States
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Asan Medical Center
Seoul, South Korea
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Chia-Yi Christian Hospital
Chiayi City, 60002, Taiwan
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Chung-Ho Memorial Hospital
Kaohsiung City, 83301, Taiwan
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Henry Ford Health System
Detroit, Michigan, 48202, United States
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ID Care
Hillsborough, New Jersey, 08844, United States
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Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, 83301, Taiwan
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Medical Center of Limited Liability Company Harmoniya Krasy
Kyiv, 01135, Ukraine
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Nepean Hospital
Kingswood, New South Wales, 2747, Australia
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Prince of Wales Hospital, The Chinese University of Hong Kong
Hong Kong, Hong Kong
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Pusan National University Hospital
Pusan, Republic of Korea, 49241, South Korea
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Queen Mary Hospital
Hong Kong, Hong Kong
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Research and Education, Inc.
San Diego, California, 92105, United States
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St Vincent's Hospital Melbourne
Melbourne, Victoria, 3065, Australia
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University of Miami Miller School of Medicine
Miami, Florida, 33136, United States
Conditions
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