Immune cell therapy shows promise for Tough-to-Treat lymphoma

NCT ID NCT04673617

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tested a new therapy called AB-101, made from natural killer (NK) cells, in 45 people with B-cell non-Hodgkin lymphoma that had come back or stopped responding to treatment. The study looked at AB-101 alone or combined with other drugs like rituximab or chemotherapy. The goal was to check safety and see if the treatment could shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AB-101 (natural killer cell therapy)

What this could lead to

If successful, this could lead to a new treatment option for patients with hard-to-treat B-cell non-Hodgkin lymphoma that has not responded to standard therapies.

What could go wrong

This is an early-phase trial with only 45 participants, so results may not apply to all patients. The therapy may cause side effects or fail to show meaningful anti-cancer activity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell non-Hodgkin lymphoma lymphoma non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Artiva Clinical Trial Site

    Birmingham, Alabama, 35249, United States

  • Artiva Clinical Trial Site

    Tucson, Arizona, 85719, United States

  • Artiva Clinical Trial Site

    Orange, California, 92868, United States

  • Artiva Clinical Trial Site

    San Diego, California, 92093, United States

  • Artiva Clinical Trial Site

    Gainesville, Florida, 32608, United States

  • Artiva Clinical Trial Site

    Atlanta, Georgia, 30342, United States

  • Artiva Clinical Trial Site

    Chicago, Illinois, 60612, United States

  • Artiva Clinical Trial Site

    Iowa City, Iowa, 52242, United States

  • Artiva Clinical Trial Site

    Wichita, Kansas, 67214, United States

  • Artiva Clinical Trial Site

    Louisville, Kentucky, 40241, United States

  • Artiva Clinical Trial Site

    Detroit, Michigan, 48201, United States

  • Artiva Clinical Trial Site

    Lake Success, New York, 11042, United States

  • Artiva Clinical Trial Site

    New York, New York, 11021, United States

  • Artiva Clinical Trial Site

    Columbus, Ohio, 43214, United States

  • Artiva Clinical Trial Site

    Portland, Oregon, 97239, United States

  • Artiva Clinical Trial Site

    Philadelphia, Pennsylvania, 19107, United States

  • Artiva Clinical Trial Site

    Philadelphia, Pennsylvania, 19111, United States

  • Artiva Clinical Trial Site

    Providence, Rhode Island, 02903, United States

  • Artiva Clinical Trial Site

    Dallas, Texas, 75246, United States

  • Artiva Clinical Trial Site

    Salt Lake City, Utah, 84112, United States

  • Artiva Clinical Trial Site

    Richmond, Virginia, 23298, United States