Gene therapy trial hopes to slow rare muscle disease

NCT ID NCT05230459

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study tests a single dose of a gene therapy called AB-1003 in 10 adults with a rare genetic muscle disease (LGMD2I/R9) that causes progressive weakness. The main goal is to check safety, not yet to prove it works. Participants must be able to walk 10 meters in under 30 seconds.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Kennedy Krieger Institute

    RECRUITING

    Baltimore, Maryland, 21205, United States

    Contact

    Contact Email: •••••@•••••

  • University of California - Irvine

    RECRUITING

    Irvine, California, 92697, United States

    Contact

    Contact Email: •••••@•••••

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Email: •••••@•••••

    Contact

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Email: •••••@•••••

    Contact

  • University of Washington Medical Center

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact

    Contact Email: •••••@•••••

  • VCU

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Email: •••••@•••••

    Contact

Conditions

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