Experimental gene therapy targets Parkinson's motor symptoms

NCT ID NCT04167540

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This early-stage study tests whether a gene therapy called AAV2-GDNF is safe for people with Parkinson's disease. The treatment delivers a protein that helps protect brain cells involved in movement. Eleven adults with mild to severe Parkinson's will receive the therapy and be monitored for side effects and changes in motor symptoms.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PARKINSON'S DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • The Ohio State University Medical Center

    Columbus, Ohio, 43210, United States

  • University of California Irvine

    Irvine, California, 92697, United States

  • University of California San Francisco

    San Francisco, California, 94103, United States

Conditions

Explore the condition pages connected to this study.