New hope for advanced HER2 cancers? early trial of A166 underway

NCT ID NCT05311397

First seen Nov 17, 2025 · Last updated Apr 24, 2026 · Updated 18 times

Summary

This early-phase study tests a new drug called A166 in 120 adults with advanced HER2-expressing solid tumors (like breast cancer) that cannot be removed by surgery or have spread. The main goal is to check safety and find the right dose, while also seeing if tumors shrink. Participants must have already tried standard treatments without success.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200032, China

Conditions

Explore the condition pages connected to this study.