New vaginal ring shows promise for Long-Term HIV prevention

NCT ID NCT05041699

First seen Apr 06, 2026 · Last updated May 03, 2026 · Updated 2 times

Summary

This early-stage study tested a vaginal ring that slowly releases two drugs (dapivirine and levonorgestrel) over 90 days in 40 healthy HIV-negative women. The goal was to see how the body absorbs the drugs, check for safety, and monitor any changes in bleeding. The ring is designed to potentially prevent HIV and offer contraception, but this study focused on gathering initial safety and drug-level data.

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Contacts and locations

Locations

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • UPMC Magee-Womens Hospital, Center for Family Planning Research

    Pittsburgh, Pennsylvania, 15213-3180, United States

Conditions

Explore the condition pages connected to this study.