Breast cancer radiation cut to just 9 days in new trial

NCT ID NCT03345420

First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 41 times

Summary

This phase II trial tested a 9-day course of whole breast radiation (hypofractionated radiotherapy) in 102 patients with early-stage breast cancer (stages 0-IIB). The goal was to see if a shorter treatment schedule could maintain good cosmetic outcomes and quality of life while reducing side effects. Participants received higher daily doses over fewer days compared to standard radiation.

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Contacts and locations

Locations

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hypofractionated radiation therapy

What this could lead to

If successful, this could offer a shorter, more convenient radiation schedule for early breast cancer patients with fewer side effects and good cosmetic results.

What could go wrong

This is a phase II trial with only 102 participants, so results are preliminary. The shorter schedule may not be as effective or well-tolerated in larger, more diverse populations.

Conditions

The condition(s) this trial relates to.

breast carcinoma in situ breast neoplasm ductal breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.