New PET scan agent spots prostate cancer missed by standard tests

NCT ID NCT05407311

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 study tested a new radioactive imaging agent called 64Cu-SAR-BBN in 53 men with prostate cancer that had returned after treatment but was not visible on standard PSMA PET scans. The goal was to see if this agent could safely and accurately detect where the cancer had recurred. Results could help doctors find hidden cancer spots and choose better treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
64Cu-SAR-BBN (a radioactive imaging agent)
What this could lead to
If successful, this could provide a new way to detect prostate cancer recurrence in patients who don't show up on standard PSMA scans, helping guide treatment decisions.
What could go wrong
This is a small, early-phase study (53 participants) focused on imaging accuracy, not treatment. The agent may not detect all recurrences, and results need confirmation in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bamf Health, Inc

    Grand Rapids, Michigan, 49503, United States

  • Biogenix Molecular

    Miami, Florida, 33165, United States

  • Carolina Urologic Research Center

    Myrtle Beach, South Carolina, 29572, United States

  • GU Research Network

    Omaha, Nebraska, 68130, United States

  • St Louis University Hospital

    St Louis, Missouri, 63104, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Tower Urology

    Los Angeles, California, 90048, United States

  • Urology San Antonio

    San Antonio, Texas, 78258, United States

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