Psychedelic 5-MeO-DMT infused in healthy brains: first safety data coming

NCT ID NCT07444788

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing how safe and tolerable intravenous 5-MeO-DMT is in 40 healthy adults aged 25-65. Participants receive either a low dose of the psychedelic or a placebo, and researchers monitor their subjective experiences, vital signs, and side effects. The goal is to gather basic safety and drug-effect data, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

5-MeO-DMT (a psychedelic compound)

What this could lead to

If successful, this study could help establish safe dosing guidelines for 5-MeO-DMT in future therapeutic research.

What could go wrong

This is an early Phase 1 safety study in healthy volunteers, not a treatment trial. The drug may cause unpleasant psychological or physical effects, and results may not translate to patient populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital Basel

    RECRUITING

    Basel, Canton of Basel-City, 4056, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••