New Antibody-Drug conjugate 3H-10000 enters human trials for Hard-to-Treat cancers

NCT ID NCT07354711

First seen Jan 22, 2026 · Last updated Jun 23, 2026 · Updated 23 times

Summary

This study tests a new drug called 3H-10000, which is an antibody-drug conjugate designed to target and kill cancer cells. It is for people with advanced lung or stomach cancer that cannot be removed by surgery or has spread. The trial will enroll 170 participants to find the safest dose and see if the drug shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

3H-10000 (an antibody-drug conjugate targeting FGFR2b)

What this could lead to

If successful, this could lead to a new treatment option for people with advanced lung or stomach cancer that has not responded to other therapies.

What could go wrong

This is an early-phase trial (Phase I/II) with only 170 participants, so the drug may not prove effective or safe enough for wider use. Side effects could be significant.

Conditions

The condition(s) this trial relates to.

gastric neoplasm lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.