Scientists 3D print a tiny spine model to unravel back pain

NCT ID NCT07250126

Recruiting now Knowledge-focused Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to create a realistic 3D bioprinted model of a spinal disc using human cells from five patients undergoing spine surgery. Researchers will compare the gene activity of cells in the model to real disc cells to see how well the model mimics the body. The goal is to develop a better tool for studying degenerative disc disease and testing future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to more realistic lab models for studying spine disease and testing potential treatments without using animals.
What could go wrong: This is a very early, small study (5 people) focused on building a model, not testing a treatment. The model may not fully mimic real human spine conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENRATIVE DISC DISEASE

Contacts and locations

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Locations

IRCCS Ospedale Galeazzi-Sant'Ambrogio
RECRUITING

Milan, MI, 20157, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

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