New hope for tough-to-treat colon cancer? drug cocktail enters human trials

NCT ID NCT05627635

First seen Nov 11, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This early-stage trial tests a combination of chemotherapy (FOLFOX), a blood-vessel blocker (bevacizumab), and two immunotherapy drugs (botensilimab and balstilimab) in 20 people with a type of advanced colorectal cancer called MSS that has spread. The goal is to see if this mix is safe and can shrink tumors or slow the disease. Participants must have stable health and a life expectancy of at least 3 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.