Could a nerve drug reverse botulism paralysis? small trial hints at hope
NCT ID NCT01441557
First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 25 times
Summary
This study tested a medicine called 3,4-diaminopyridine (FIRDAPSE) in people with severe botulism who needed a breathing machine. The goal was to see if the drug could improve muscle strength and breathing. Only 3 people took part, and researchers measured changes in nerve signals and breathing before and after the drug. The results help guide future research but are too small to draw firm conclusions.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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CHU
Amiens, 80000, France
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.