Could a sugar imposter stop seizures?
NCT ID NCT05605301
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested how a pill called 2-deoxy-D-glucose (2DG) is absorbed and processed in 9 adults with epilepsy. 2DG is similar to sugar but can't be used for energy, so it may 'clog' the brain's fuel supply during a seizure and stop it. Researchers measured drug levels in the blood after different doses to understand safety and dosing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 2-deoxy-D-glucose (2DG)
- What this could lead to
- If successful, this could point toward a new way to stop seizures by blocking the brain's energy use during a seizure.
- What could go wrong
- This is a very small, early-phase study with only 9 people, focused on drug levels and safety, not on stopping seizures. It may not lead to an effective treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for EPILEPSY; SEIZURE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Virginia School of Medicine
Charlottesville, Virginia, 22908, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.