Zhongshan Ophthalmic Center, Sun Yat-sen University

This early-stage study tests a new gene therapy drug, ZVS106e, for people with Stargardt disease caused by specific genetic changes. Nine participants aged 8 and older will receive a single injection under the retina in one eye. The main goal is to check safety over 52 weeks, whi…

This study looks at whether placing a small support ring (capsular tension ring) during cataract surgery helps keep the artificial lens more stable in people who also have retinitis pigmentosa, an eye disease that can weaken the lens's natural support. About 88 adults with both c…

This study tests whether adding the drug 5-fluorouracil (5-FU) during tear duct surgery helps prevent scarring and improves outcomes for people with small tear sacs and blocked tear ducts. About 100 adults will be randomly assigned to receive either 5-FU or a placebo during the p…

This study tests if injecting the drug rituximab directly into eye tumors works as well as standard radiation therapy for a rare type of eye lymphoma (MALT lymphoma). About 108 adults aged 18-75 with early-stage disease will be randomly assigned to one of the two treatments. The …

This study tests whether a drug called Anrikefon can control pain after eye surgery as well as a standard painkiller, but with fewer side effects like drowsiness. About 204 adults having eye surgery under general anesthesia will receive either Anrikefon or the standard drug durin…

This study tests whether a web-based visual training program can improve eyesight and depth perception in children aged 4-12 who have had surgery for a rare lens dislocation condition called congenital ectopia lentis. About 82 children will be randomly assigned to receive the tra…

This study uses advanced eye scans (OCT and OCTA) to look at the retina and choroid—the layers at the back of the eye—in people with different types of glaucoma. Researchers will compare 132 participants, including healthy volunteers and those with angle-closure or open-angle gla…

This study is following 5,000 adults aged 65 and older to learn how eye diseases develop and progress over time. Researchers will collect medical history, eye exams, and biological samples to build a comprehensive database. The goal is to create a personalized risk prediction too…

This study follows 73 people aged 3 to 60 who are already scheduled for surgery to fix droopy eyelids (congenital ptosis). Researchers want to see if the operation improves eyesight, depth perception, and quality of life over six months. Participants will take vision tests and fi…

This study looks at a new way to provide eye care to children in rural China. It will involve about 20,000 kids aged 3 to 18 from schools in several counties. The goal is to see if a coordinated program across local health centers and schools can improve eye screening rates and h…

This study watches 300 cataract patients during surgery to see if where the surgeon places the phaco tip (above the lens, at the iris, or inside the lens) changes how the cornea heals and how quickly vision improves. Participants get special imaging during surgery and follow-up e…

This study uses special cameras to watch how eye tissues heal after minimally invasive glaucoma surgery. Researchers will follow 300 glaucoma patients to measure changes in the eye's drainage angle over time. The goal is to learn more about healing patterns and help improve futur…