West China Hospital

This early-stage trial tests a new type of vaccine made from engineered mitochondria, designed to help the immune system attack cancer cells. It is for people with advanced solid tumors who have no other standard treatment options. The main goal is to check safety, but researcher…

This early-phase study tests whether a nasal vaccine (WSK-IM05) combined with an immunotherapy drug (tislelizumab) can safely shrink HPV-positive throat tumors before surgery. Nine adults with newly diagnosed, resectable cancer will receive two cycles of the combination, then und…

This early-phase trial tests a single injection of JWK010 gene therapy in 18 children aged 5 to 12 with oculocutaneous albinism type 1 (OCA1), a condition causing little to no pigment in the eyes, skin, and hair. The therapy is designed to help eye cells produce the missing pigme…

This early-phase study tests the safety of a new treatment made from immune cells (macrophages) that are reprogrammed to fight cancer. The treatment is injected directly into tumors in adults aged 18-65 with advanced solid tumors who have no other options. The goal is to see if i…

This early-stage trial tests a personalized vaccine made from a patient's own tumor cells, modified to boost the immune system's attack on advanced colorectal cancer that hasn't responded to standard treatments. About 9 adults will receive several vaccine injections over months, …

This study tests a new imaging tool that uses folic acid and tiny carbon dots to make liver cancer cells glow under a special camera. After surgery to remove liver cancer, the removed tissue is treated with these dots and scanned to see if the glow can help find cancer edges and …

This study tests a special cream made from amino acids to prevent skin damage caused by radiation therapy in people with head and neck cancer. The cream aims to reduce redness, pain, and peeling of the skin. About 40 participants will be randomly assigned to receive the cream or …

This study reviews medical records of 2,000 adults who had liver surgery with their gallbladder left in place. Researchers want to see if temporarily clamping the liver's blood supply (called the Pringle maneuver) makes patients more likely to develop gallstones, inflammation, or…