University Of Siena
Clinical trials sponsored by University Of Siena, explained in plain language.
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Mouthwash showdown: which rinse best fights gum disease?
Disease control CompletedThis study tested two mouthwashes—one with 0.12% chlorhexidine and another with a lower dose of chlorhexidine plus cetylpyridinium chloride—to see which better controls gum inflammation and bacteria in people with gum disease. 72 adults used one of the rinses for a month after a …
Phase: NA • Sponsor: University of Siena • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Floss vs brush: which keeps implant gums healthier?
Disease control CompletedThis study tested two cleaning tools—superfloss and interdental brushes—in 52 adults with gum inflammation around dental implants. Each person used one tool daily along with an electric toothbrush. Researchers measured plaque and bleeding to see which worked better. The goal is t…
Phase: NA • Sponsor: University of Siena • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Your mental health could be linked to tooth infections, study finds
Knowledge-focused CompletedThis study looked at 120 adults to see if anxiety and depression are linked to a common tooth infection called apical periodontitis. Participants had dental exams and filled out questionnaires about their mental health. The goal was to better understand how emotional well-being a…
Sponsor: University of Siena • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Gum therapy may ease teeth grinding, small study hints
Knowledge-focused CompletedThis study tested whether treating severe gum disease (periodontitis) with a deep cleaning procedure could also reduce teeth grinding (bruxism) during the day and night. Forty adults with advanced gum disease or healthy gums took part. Researchers measured grinding events before …
Phase: NA • Sponsor: University of Siena • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Dental implant disease: patients speak out in new survey
Knowledge-focused CompletedThis completed study looked at how people with dental implant problems (like gum inflammation or infection around the implant) perceive their condition and how it affects their daily life. Researchers gave 148 patients two questionnaires to measure their awareness and quality of …
Sponsor: University of Siena • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:48 UTC
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Gum disease and nighttime teeth grinding: is there a connection?
Knowledge-focused CompletedThis completed study looked at whether people with advanced gum disease (periodontitis) also grind or clench their teeth more during sleep. Researchers used a small portable device to measure muscle activity in the jaw over 24 hours in 40 adults, half with severe gum disease and …
Sponsor: University of Siena • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:30 UTC