Penta Foundation
Clinical trials sponsored by Penta Foundation, explained in plain language.
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Could a Two-Drug pill replace triple therapy for kids with HIV?
Disease control OngoingThis study tests whether a two-drug combination (dolutegravir and lamivudine) is as safe and effective as the standard three-drug HIV treatment for children aged 2 to 15. About 386 children who already have undetectable HIV levels will take either the two-drug pill or their usual…
Phase: PHASE2, PHASE3 • Sponsor: PENTA Foundation • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New hope for kids with Drug-Resistant HIV: SHIELD trial launches
Disease control OngoingThis study tests a new HIV medicine called fostemsavir in children and teens (ages 6-17) whose current HIV drugs are no longer working because the virus has become resistant. The goal is to see if the medicine is safe and can lower the amount of HIV in the blood when taken with o…
Phase: PHASE1, PHASE2 • Sponsor: PENTA Foundation • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New HIV pill for kids pulled before start
Disease control TerminatedThis study aimed to test a new solid tablet combining two HIV drugs (darunavir and ritonavir) for children aged 3 and older weighing 10-25 kg. The goal was to find the right dose and check safety and acceptability. However, the trial was withdrawn before any participants were enr…
Phase: PHASE1, PHASE2 • Sponsor: PENTA Foundation • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC