Orchestra Biomed, Inc

This study tests a new balloon coated with sirolimus (Virtue SAB) against an existing balloon coated with paclitaxel (AGENT DCB) for treating in-stent restenosis — when a previously placed stent in a heart artery becomes blocked again. About 740 people with one re-narrowed stent …

This study tests a special pacemaker setting designed to lower blood pressure in people with hypertension. About 500 adults who already have or need a pacemaker will take part. The goal is to see if this new setting safely reduces average blood pressure over 24 hours, compared to…