Janssen Pharmaceutica N.v., Belgium

This study is testing whether an experimental vaccine can slow or prevent cognitive decline in people who have early Alzheimer's-related brain changes but no memory symptoms yet. About 500 participants will receive either the vaccine or a placebo and be followed for about 4 years…

This study is observing over 1,300 people with psoriatic arthritis who are starting one of two types of injectable medications (guselkumab or an IL-17 inhibitor) as part of their regular doctor's care. The main goal is to see how long patients continue taking these medications an…

This large, late-stage study is testing if adding the drug apalutamide to standard radiation and hormone therapy is better at delaying the spread of prostate cancer in high-risk patients who have already had surgery. It will involve about 693 men and use advanced PET scans to clo…