Janssen-cilag Ltd.

This study tests a drug called guselkumab in 120 people with Crohn's disease to see if it can heal all layers of the digestive tract. The main goal is to check healing using an MRI scan after 48 weeks of treatment. Participants must have active Crohn's disease and will receive th…

This study tests a drug called guselkumab in people with Crohn's disease who have abnormal tunnels (fistulas) near the anus. The goal is to see if the drug can close these fistulas and prevent new ones, using MRI scans to confirm healing. About 288 adults who have not responded t…

This study follows about 500 men with advanced prostate cancer that still responds to hormone therapy. Researchers are comparing two drug combinations (apalutamide or enzalutamide plus standard hormone therapy) to see how well they work in real-world settings. The goal is to unde…