Polio virus turned against skin cancer in new trial
Disease control
Completed
This Phase 2 trial tested a modified polio virus called lerapolturev, alone or combined with an immunotherapy drug, in 27 adults with advanced melanoma that had stopped responding to standard PD-1 therapy. The virus was injected directly into tumors to trigger an immune attack. R…
Phase: PHASE2 • Sponsor: Istari Oncology, Inc. • Aim: Disease control
Last updated Jun 26, 2026 19:20 UTC