Icahn School Of Medicine At Mount Sinai

This trial tests whether replacing some of the usual diet with navy beans — without changing total calories — is a practical and acceptable way to help manage metabolic dysfunction-associated steatotic liver disease (MASLD) in adults with intermediate-stage liver fibrosis. Forty …

This study compares two ways to manage diabetes after hospital discharge: using a continuous glucose monitor (CGM) versus standard fingerstick checks. About 64 adults with type 2 or steroid-induced diabetes who need insulin after leaving the hospital will wear a sensor for 28 day…

This study tests whether sending patients home on the same day of surgery, with follow-up care via phone calls, home visits, and a mobile app, is as safe and less costly than keeping them in the hospital overnight. The trial includes adults in Uganda having low-risk procedures su…

This phase 2 trial tests whether a combination of three drugs—valacyclovir, celecoxib, and Paxlovid—can reduce Long COVID symptoms in adults. About 150 participants aged 18-65 with diagnosed Long COVID will receive either the drug combo or a placebo. The main goal is to see if th…

This study tests whether group care—where patients meet together with health workers for education and check-ups—can improve control of high blood pressure and diabetes in Nepal. Over 1,100 adults from 37 health facilities will be assigned to standard care, low-intensity group ca…

This pilot trial tests a community-based program designed to help Chinese immigrants aged 45-75 get up-to-date on colorectal and breast cancer screening. The program includes a group education session led by a community health worker and personalized help navigating the healthcar…

This study tests whether a drug called sotagliflozin can prevent heart, muscle, and fat damage caused by a common type of chemotherapy (anthracycline) in people with newly diagnosed lymphoma. About 60 adults who are scheduled to receive high-dose anthracycline will take either th…

This study tests whether high-intensity focused ultrasound (HIFU) can safely and effectively treat urinary symptoms caused by an enlarged prostate. Seventeen men aged 45 to 80 with moderate to severe symptoms will receive a single HIFU treatment using a probe placed in the rectum…

This trial asks whether keeping the knee slightly bent for a few hours after knee replacement surgery improves recovery compared to the usual straight position. About 150 adults scheduled for a knee replacement will be randomly assigned to either have their knee positioned at a 6…

This trial tests two sedatives—remimazolam and dexmedetomidine—to see which better relieves anxiety while keeping pregnant women comfortable and safe during spinal anesthesia placement for scheduled C-sections. The study includes 150 women at full term and measures success by pat…

This early study tests whether a low-level magnetic therapy device, used at home, is safe and practical for people with cognitive issues from brain injury, Long COVID, or Alzheimer's. About 30 adults will use the device regularly and complete computer-based thinking tests. The go…

This study tests whether a combination of real-time brain training (using a wearable brain scanner called fNIRS) and personalized text messages can help women with bulimia nervosa improve self-control and reduce binge eating. Forty women aged 18-55 will receive either real or sha…

This study tests a group therapy program called HOPE-LC~Español for Spanish-speaking adults with Long COVID. The program teaches coping skills and resilience. Researchers will enroll 25 people in Queens to see if the program is helpful and practical.

This study tests whether a 5-week heart rate variability biofeedback program can reduce symptoms in people with ulcerative colitis who are currently having a flare but show no active inflammation. Twenty-three adults will practice daily breathing exercises using a device and be f…

This study tests a flexible palliative care program for people with advanced heart failure or certain cancers. The program adds more team members—like a social worker or nurse—as symptoms get worse. The goal is to improve quality of life and match care to each person's changing n…

This study follows people with Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) over time to learn how the condition progresses and affects daily life. Researchers will collect health data and patient feedback to identify patterns and potential markers of the disease. The goal i…

This study tracks how a pregnant person's heart and lungs change over the course of pregnancy and after childbirth. Researchers will use non-invasive tests to measure blood flow and airway function, aiming to understand how these changes relate to the development of preeclampsia,…

This study uses a quick, non-invasive breath test (FeNO) to measure airway inflammation in adults with asthma who are treated in primary care or community specialty clinics. The goal is to see how many patients have type 2 inflammation, which often goes undetected. Researchers ho…

This pilot study will test whether continuous glucose monitors (CGMs) can accurately track blood sugar levels during scheduled C-sections in 150 women without diabetes. The goal is to understand normal glucose patterns during surgery and see if they relate to complications like w…

This study tests a virtual education program called LIFT-ECHO, where non-specialist doctors learn from experts how to better manage chronic intestinal failure. Researchers will enroll 150 patients and their doctors, tracking quality of life and disease activity over 12 months. Th…

This small study will test whether a stomach ultrasound can work in people who have already had bariatric surgery. Ten adults scheduled for another surgery will have their stomachs scanned before and after the procedure. The goal is to see if ultrasound can measure stomach size a…