Icahn School Of Medicine At Mount Sinai

This phase 2 trial tests whether a combination of three drugs—valacyclovir, celecoxib, and Paxlovid—can reduce Long COVID symptoms in adults. About 150 participants aged 18-65 with diagnosed Long COVID will receive either the drug combo or a placebo. The main goal is to see if th…

This study compares two ways to manage diabetes after hospital discharge: using a continuous glucose monitor (CGM) versus standard fingerstick checks. About 64 adults with type 2 or steroid-induced diabetes who need insulin after leaving the hospital will wear a sensor for 28 day…

This study tests whether using special coils to block blood vessels can help treat chronic subdural hematoma, a type of brain bleed common in older adults. Researchers will enroll 150 people to see if the procedure reduces bleeding and prevents the need for repeat surgery. The ap…

This study tests whether group care—where patients meet together with health workers for education and check-ups—can improve control of high blood pressure and diabetes in Nepal. Over 1,100 adults from 37 health facilities will be assigned to standard care, low-intensity group ca…

This study tests a device called the Numen SILK coil, which is placed into the middle meningeal artery to block blood flow and help resolve chronic subdural hematoma—a slow brain bleed common in older adults. Researchers will enroll 100 people to see if this minimally invasive pr…

This study tests whether a drug called sotagliflozin can prevent heart, muscle, and fat damage caused by a common type of chemotherapy (anthracycline) in people with newly diagnosed lymphoma. About 60 adults who are scheduled to receive high-dose anthracycline will take either th…

This trial tests two sedatives—remimazolam and dexmedetomidine—to see which better relieves anxiety while keeping pregnant women comfortable and safe during spinal anesthesia placement for scheduled C-sections. The study includes 150 women at full term and measures success by pat…

This early study tests whether a low-level magnetic therapy device, used at home, is safe and practical for people with cognitive issues from brain injury, Long COVID, or Alzheimer's. About 30 adults will use the device regularly and complete computer-based thinking tests. The go…

This study tests whether a combination of real-time brain training (using a wearable brain scanner called fNIRS) and personalized text messages can help women with bulimia nervosa improve self-control and reduce binge eating. Forty women aged 18-55 will receive either real or sha…

This study tests a group therapy program called HOPE-LC~Español for Spanish-speaking adults with Long COVID. The program teaches coping skills and resilience. Researchers will enroll 25 people in Queens to see if the program is helpful and practical.

This study tests whether high-intensity focused ultrasound (HIFU) can safely and effectively treat urinary symptoms caused by an enlarged prostate. Seventeen men aged 45 to 80 with moderate to severe symptoms will receive a single HIFU treatment using a probe placed in the rectum…

This study tests whether a 5-week heart rate variability biofeedback program can reduce symptoms in people with ulcerative colitis who are currently having a flare but show no active inflammation. Twenty-three adults will practice daily breathing exercises using a device and be f…

This study tests a flexible palliative care program for people with advanced heart failure or certain cancers. The program adds more team members—like a social worker or nurse—as symptoms get worse. The goal is to improve quality of life and match care to each person's changing n…

This study uses a quick, non-invasive breath test (FeNO) to measure airway inflammation in adults with asthma who are treated in primary care or community specialty clinics. The goal is to see how many patients have type 2 inflammation, which often goes undetected. Researchers ho…

This pilot study will test whether continuous glucose monitors (CGMs) can accurately track blood sugar levels during scheduled C-sections in 150 women without diabetes. The goal is to understand normal glucose patterns during surgery and see if they relate to complications like w…

This observational study will follow 30 multiple myeloma patients receiving a standard CAR-T therapy called cilta-cel. Researchers will collect blood, bone marrow, and other samples to find biomarkers linked to rare toxicities like nerve damage, blood issues, and gut problems. Th…

This study tests a virtual education program called LIFT-ECHO, where non-specialist doctors learn from experts how to better manage chronic intestinal failure. Researchers will enroll 150 patients and their doctors, tracking quality of life and disease activity over 12 months. Th…

This small study will test whether a stomach ultrasound can work in people who have already had bariatric surgery. Ten adults scheduled for another surgery will have their stomachs scanned before and after the procedure. The goal is to see if ultrasound can measure stomach size a…