Hong Kong Children's Hospital

This Phase 2 trial tests a new method to improve stem cell transplants for people with blood disorders who lack a fully matched donor. Researchers will give patients specially processed donor immune cells (CD62L-depleted lymphocytes) alongside a T-cell depleted stem cell transpla…

This phase 2 trial tests a combination of four immune-based treatments for children whose neuroblastoma has returned or not responded to standard care. The therapy includes natural killer cells from a relative, two antibodies (dinutuximab beta and naxitamab), immune-boosting cyto…

This study compares a new radiation technique called total lymphoid irradiation (TLI) to the standard total body irradiation (TBI) for children aged 0-18 who need a stem cell transplant from a half-matched donor. The goal is to see if TLI reduces complications like graft-versus-h…