Groupe Oncologie Radiotherapie Tete Et Cou

This phase 3 trial tests two experimental treatments—ivonescimab alone or with ligufalimab—against the standard drug pembrolizumab for people with advanced head and neck cancer that has come back or spread. About 780 adults with PD-L1-positive tumors will take part. The main goal…

This study tests whether adding a new drug (ficerafusp alfa) to an existing immunotherapy (nivolumab) can shrink tumors better than nivolumab alone in people with advanced head and neck cancer that stopped responding to platinum chemotherapy. About 131 adults aged 18-75 will part…