Can a pill target a Hard-to-Treat colorectal cancer?
Disease control
Not yet recruiting
This trial tests an experimental oral drug called DES-1357 in adults with metastatic colorectal cancer that has specific genetic features (dMMR or MSI-H). The study runs in three parts: first, to find a safe dose; second, to check tolerability and early signs of tumor shrinkage; …
Phase 1/2 • Sponsor: D. E. Shaw Research, LLC • Aim: Disease control
Last updated Sep 09, 2026 17:00 UTC