Clinical Hub For Interventional Research (choir)

This early-phase study tests whether adding an experimental drug (defactinib) to an approved oral treatment (decitabine/cedazuridine) is safe and tolerable for people with high-risk myelodysplastic syndromes, certain acute myeloid leukemias, or chronic myelomonocytic leukemia. Al…

This study aims to develop a faster way to test new drug combinations for acute myeloid leukemia (AML). Researchers will take blood and bone marrow samples from 25 adults with AML and grow their cancer cells in special mice. They will then test how well standard treatments work i…

This study follows 100 people aged 55 and older who have clonal hematopoiesis (CH) or possible CH, a condition where blood cells carry certain genetic changes. Researchers will monitor their health, check for risks of heart disease and blood cancers, and provide personalized supp…