Children's Hospital Medical Center, Cincinnati
Clinical trials sponsored by Children's Hospital Medical Center, Cincinnati, explained in plain language.
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Gut-Healing sugar may cut infections in transplant patients
Disease control CompletedThis study tested whether a natural sugar called 2'-fucosyllactose (2FL) is safe and helpful for people receiving a bone marrow transplant. The goal was to see if it could improve gut health, reduce harmful bacteria, and lower the risk of infections and graft-versus-host disease.…
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Apr 29, 2026 05:31 UTC
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Mom's surgery, Kid's health: new program shows promise
Disease control CompletedThis study tested a program called HALO for children aged 6-12 whose mothers had weight-loss surgery. The program helped kids learn healthier eating and activity habits. 35 families took part to see if the program could help children maintain a healthy weight.
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Apr 29, 2026 05:30 UTC
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New drug shows promise for rare stomach disorder
Disease control CompletedThis study tested a drug called dupilumab in 41 people aged 12 to 70 with eosinophilic gastritis, a condition where certain white blood cells build up in the stomach and cause pain and swelling. Participants received injections of dupilumab or a placebo every two weeks for 12 wee…
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Apr 26, 2026 20:01 UTC
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Emergency rooms get smarter about teen STI screening
Diagnosis CompletedThis study looked at how to improve testing for sexually transmitted infections (STIs) like gonorrhea and chlamydia in teenagers visiting emergency departments. Researchers compared two methods: testing only teens with certain risk factors versus offering testing to everyone. The…
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Diagnosis
Last updated Apr 26, 2026 20:00 UTC
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Toothpaste that tames transplant mouth sores?
Symptom relief CompletedThis study tested a special toothpaste containing tacrolimus to help manage painful mouth sores caused by chronic graft-versus-host disease (cGVHD) after a stem cell transplant. Seven patients aged 1 to 40 used the toothpaste alongside their regular medicines. The goal was to see…
Phase: PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Symptom relief
Last updated Apr 26, 2026 20:00 UTC
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Can a custom app help young cancer patients stick to their meds?
Knowledge-focused CompletedThis study tested a new program designed to help teens and young adults (ages 15-24) with cancer take their oral chemotherapy or preventive medications as prescribed. 70 participants were randomly assigned to either the tailored program or standard care. The main goal was to see …
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Apr 29, 2026 05:29 UTC
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Can telehealth keep kids with chronic conditions out of the ER?
Knowledge-focused CompletedThis study tested a telehealth program called GET2HOME for children with complex chronic conditions leaving the hospital. The goal was to see if the program could reduce unplanned hospital visits and improve quality of life for the child and family. Over 600 children and their fa…
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:02 UTC
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New dosing study aims to improve antibiotic use in kids with cystic fibrosis
Knowledge-focused CompletedThis study involved 8 children and teens with cystic fibrosis who had a history of MRSA infection and were receiving the antibiotic ceftaroline. Researchers measured drug levels in the blood to see if current dosing recommendations work well for this group. The goal was to gather…
Phase: PHASE4 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC