Amryt Pharma

This study tests a drug called metreleptin in children under 6 who have generalized lipodystrophy, a rare condition where the body loses fat tissue, leading to severe diabetes and high blood fats. The goal is to see if the drug safely lowers blood sugar and fat levels. About 15 c…

This study is for people with partial lipodystrophy, a rare condition where the body cannot properly store fat, leading to serious health problems. It tests the long-term safety and effectiveness of a daily injection called metreleptin. Participants must have completed a prior re…

This study follows 580 people with dystrophic or junctional epidermolysis bullosa (EB) for up to 5 years. Researchers will compare those who use Filsuvez gel with those who don't, to see if the gel affects the chance of developing skin cancer. The goal is to gather safety data, n…

This study is a registry that collects information from people with generalized or partial lipodystrophy who are taking the drug metreleptin. The goal is to track safety events like pancreatitis, liver problems, and infections in everyday medical practice. About 100 participants …