Alnylam Pharmaceuticals

This study tested the safety of a new drug called ALN-TTRSC04 in healthy volunteers. The drug is designed to treat a rare disease where a harmful protein builds up in the body. Researchers gave single, increasing doses to 96 people to see how their bodies handled it and to check …

This study tested an experimental drug called ALN-AGT01, designed to lower blood pressure in adults with mild-to-moderate hypertension. Nearly 400 participants received either the drug or a placebo for up to a year to see how well it worked and how safe it was. The goal was to se…

This study tested whether a new drug called vutrisiran could help people with hereditary transthyretin amyloidosis (hATTR), a rare disease where a faulty protein builds up and damages nerves and organs. 164 patients received injections of either vutrisiran or an existing treatmen…

This study tested an investigational drug called zilebesiran in adults with high cardiovascular risk and high blood pressure that was not well-controlled despite taking standard medications. The goal was to see if adding zilebesiran could safely lower blood pressure more effectiv…

This study tested an experimental drug called zilebesiran in adults whose high blood pressure was not well controlled by their current medication. Over 660 participants received either the new drug or a placebo as an add-on to their standard treatment. The main goal was to see if…

This early-stage study tested a new drug called ALN-AGT01 RVR in healthy adults to see if it is safe and how it moves through the body. Forty-two participants received a single dose, and researchers closely monitored them for any side effects. The main goal was to gather initial …